Hemorrhagic Fever with Renal Syndrome (HFRS)
On the heels of the report of one confirmed death in Dominica from the hantavirus , we at peepirit. Realise the serious threat to our population and after much thought go back to blogging admidst the threats and pulling down of our blogs and emails and Facebook accounts by government operatives. We are aware of the disaster in Haiti where the people were infected with various bacteria in their water and have accused the United nations and the red cross. Knowing the history of this virus which is mostly spread by rodents we hope that we are not suffering the same fate as haiti for Dominica do not have a population to control but man's heart is desperate these days we do not know what, when and where disease and viruses are coming from to dismantle our lives. Here we post instructions from the center for disease control in the United states of America as some form of education on the virus.
Where is HFRS found?
HFRS is found throughout the world. Haantan virus is widely distributed in eastern Asia, particularly in China, Russia, and Korea. Puumala virus is found in Scandinavia, western Europe, and western Russia. Dobrava virus is found primarily in the Balkans, and Seoul virus is found worldwide. Saaremaa is found in central Europe and Scandinavia. In the Americas, hantaviruses cause a different disease known as hantavirus pulmonary syndrome.
How do humans get HFRS?
Which rodents carry the hantaviruses that cause HFRS in humans?
Rodents are the natural reservoir for hantaviruses. Known carriers include the striped field mouse (Apodemus agrarius), the reservoir for both the Saaremaa and Hantaan virus; the brown or Norway rat (Rattus norvegicus), the reservoir for Seoul virus; the bank vole (Clethrionomys glareolus), the reservoir for Puumala virus; and the yellow-necked field mouse (Apodemus flavicollis), which carries Dobrava virus.
What are the symptoms of HFRS?
Symptoms of HFRS usually develop within 1 to 2 weeks after exposure to infectious material, but in rare cases, they may take up to 8 weeks to develop. Initial symptoms begin suddenly and include intense headaches, back and abdominal pain, fever, chills, nausea, and blurred vision. Individuals may have flushing of the face, inflammation or redness of the eyes, or a rash. Later symptoms can include low blood pressure, acute shock, vascular leakage, and acute kidney failure, which can cause severe fluid overload. The severity of the disease varies depending upon the virus causing the infection. Hantaan and Dobrava virus infections usually cause severe symptoms, while Seoul, Saaremaa, and Puumala virus infections are usually more moderate. Complete recovery can take weeks or months.
How is HFRS diagnosed?
Several laboratory tests are used to confirm a diagnosis of HFRS in patients with a clinical history compatible with the disease. Such patients are determined to have HFRS if they have serologic test results positive for hantavirus infection, evidence of hantavirus antigen in tissue by immunohistochemical staining and microscope examination, or evidence of hantavirus RNA sequences in blood or tissue.
How is HFRS treated?
Supportive therapy is the mainstay of care for patients with hantavirus infections. Care includes careful management of the patient’s fluid (hydration) and electrolyte (e.g., sodium, potassium, chloride) levels, maintenance of correct oxygen and blood pressure levels, and appropriate treatment of any secondary infections. Dialysis may be required to correct severe fluid overload. Intravenous ribavirin, an antiviral drug, has been shown to decrease illness and death associated with HFRS if used very early in the disease.
Is HFRS ever fatal?
Depending upon which virus is causing the HFRS, death occurs in less than 1% to as many as 15% of patients. Fatality ranges from 5-15% for HFRS caused by Hantaan virus, and it is less than 1% for disease caused by Puumala virus.
How is HFRS prevented?
Rodent control is the primary strategy for preventing hantavirus infections. Rodent populations near human communities should be controlled, and should be excluded from homes. Individuals should avoid contact with rodent urine, droppings, saliva, and nesting materials, and the safety measures described below should be followed when cleaning rodent-infested areas.
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